In engineering design of oil and gas pipelines crossing multiple rail transit routes, single application of directional drilling or pipe jacking is unable to meet relative safety requirements. In order to ensure that construction is successfully completed, studied is the combination of such two construction technologies as directional drilling and pipe jacking and analyzed and prepared are the construction process control measures. The construction scheme reduced construction difficulty, cut short construction period and saved project investment effectively. It has been found that the combination of directional drilling and pipe jacking is not only reliable technically, hut also has high economic benefit and application promotion value.