Anti-floating stability design of river bank water pump room is an important link in pump room stability design. In order to discuss characteristics of application of anti-pull-out anchor rod anchorage anti-floating stability in pump room anti-floating stability design, taking anti-floating stability design of water pump room in Yuanba Gas Field purification plant as an example, briefly described is the principle of anti-pull-out anchor rod anchorage anti-floating stability of pump room, application locations, such as in structure with higher water level in the side near water, in structure basement with higher underground water level or in areas with complete, solid and thick bed rock. Put forward are some design essentials of anti-pull-out anchor rod anchorage anti-floating stability, which can provide useful reference for engineering design and construction in similar projects.