In the hot work construction of pipe containing hydrocarbon using hot-tapping and plugging techniques, hot tap operation is very often not successful due to the high static pressure of the pipeline. At present, the available hot tapping and plugging equipment is not suitable for ultra-high pressure. In view of the above problems, building on the oil pipeline plugging technology accumulated so far, this paper presents a complete set of multiple plugging construction method developed for pipeline with big elevation drop and ultra-high pressure oil pipeline under shutdown condition. The core process is to appropriately divide one ultra-high pressure plugging operation into two or more plugging operations to ensure that each plugging stage’s back pressure is within the range of high-pressure plugging operation pressure (2.5~5 MPa), thereby minimising the risks and potential safety hazards associated with ultra-high pressure plugging. On the premise that the expected construction quality is guaranteed, this multiple pugging techniques shortens the time frame taken for the plugging operation and reduces the construction cost. This paper provides a useful reference for the safe reconstruction of oil and gas pipelines having big elevation drop and ultra-high pressure.