The process of hydrogen sulfide removal by wet oxidation of chelated iron is widely used in China. In the recovery and oxidation of acid gas from desulfurization process, the sulfur slurry and other related substances generated by the chelated iron desulfurization process may block the aeration air piping, resulting in the failure of the aeration air purging, thus affecting the service life of the desulfurization equipment. In order to solve the above problem, this paper analyzed chemical dosing amount and parameters of the H2S process of the chelated iron wet oxidation process and aeration air purge mode, and conducted large number of field tests over a long period of time on the cone of the absorption oxidation tower. The flow pattern of the cone section is also analyzed by numerical simulation in combination with actual field test results. By optimizing the chemical dosing amount and parameters, duration and angle of purging in actual operation, suggestions are put forward to reduce or avoid the event of sulfur slurry blocking the aeration air piping. This research result could provide references for reducing the clogging of aeration air piping in the process of H2S removal by chelated iron wet oxidation.