The Xujiahe formation in western Sichuan has fractured high temperature and high pressure gas reservoirs with high single well water production and low gas-liquid ratio. In order to accurately predict wellbore pressure, provide important basis for judging wellbore liquid accumulation, optimizing production system of gas well and making out drainage technology scheme, Using 38 wells of measured flow pressure data from Xujiahe formation gas reservoir in western Sichuan province, the bottomhole pressure predicted by 9 gas-liquid two-phase tubular flow pressure drop models commonly used were compared and analyzed. The results show that water yield and gas-liquid ratio are the main factors that influence the relative error of wellbore pressure drop model; Ansari and GA models are suitable for gas wells with gas-liquid ratio less than 400 m3/m3 and water production between 100 and 300 m3; while BBO and DR models are suitable for gas wells with gas-liquid ratio less than 240 m3/m3 and water production between 100 and 300 m3; Gray and HB models are suitable for gas wells with gas-liquid ratio less than 1 500 m3/m3 and water production less than 110 m3. According to the wellbore pressure data predicted by the optimized wellbore pressure drop model, the technical measures are in line with the actual gas well and the measures have achieved good results. The results of the study are important for improving the accuracy of wellbore pressure calculation, and can provide a basis for optimizing the production allocation of gas wells and formulating drainage and recovery plan.