Hydrogen energy is a kind of clean energy with zero carbon emission and various applications, which is expected to become an important driving force in promoting China’s energy transformation. Pipeline transportation of hydrogen-blended natural gas can make full use of existing natural gas pipeline network facilities, solve the problem of wastage of surplus renewable energy that is above the power demand, and promote the development of low-carbon economy. In this paper, the research progress of the pipeline transportation of hydrogen-blended natural gas at home and abroad was systematically summarized, and the feasibility and main challenges expounded as well. The research shows that after blending with hydrogen, the Wobbe index and combustion potential of the mixed gas decrease. When the hydrogen-blended ratio is less than 20 %, the gas requirements of domestic consumers can be satisfied. The probability of hydrogen embrittlement increases with the increase of pipe grade, and the medium-low pressure natural gas pipeline network is more suitable for hydrogen-blended gas transportation. The working components of the centrifugal compressor are in direct contact with hydrogen, and are therefore more susceptible to hydrogen corrosion. Compressor surge is prone to occur as the combined working range with the pipeline network is narrowed. The operating conditions can be stabilized by increasing the operating pressure of the pipeline network. At present, there is still a gap in domestic and foreign regulations for pipeline transportation of hydrogen-blended natural gas, and the related projects are mostly carried out according to the design specifications of pure hydrogen pipelines or natural gas pipelines. Hydrogen-blended gas transportation using existing natural gas pipeline network enjoys a promising future. It is suggested to carry out in-depth technical application demonstration and speed up the introduction of relevant professional norms to promote the steady development of hydrogen energy industry.