As the critical component of safety protection forimportant equipment, the effect of piping strainers can’t be ignored. In order to avoid safety issue in production due to piping strainers’ defect, it is necessary to conduct a comprehensive and detailed analysis to improve the design and technical requirements. Combining with the current standards and practical engineering experience, this article discusses some problem when piping strainers are applied in engineering design phase, such as screen mesh, screen strength checking, screen installation, strainer operation and maintenance, drain outlet setting, etc. Through detailed investigation into the root of these problems, this article puts forward targeted and feasible solutions, and provides reference forsimilar project design.