日濮洛原油管道全长798 km,沿线6 km内最大高差达到132 m,在大落差管段采用水隔离段后投油方式投产时，容易出现高点积气、低点积水等问题,威胁投产的安全。基于OLGA软件建立日濮洛原油管道投产仿真模型,分析水顶气、油顶水投产过程中泵站压力变化,以及不同管道输量和充水长度对翻越点压力、持液率、低点持水率的影响。分析结果表明,投产工况为管道输量1 440 m3/h时,最小充水长度达到70 km,管道翻越点压力、持液率、低点持水率的变化情况可以满足安全需求,建议在条件允许情况下,将充水长度扩大至站间距或全线长度,可进一步提高投产试运行的安全性。研究结果可有效指导其他原油管道投产方案的制定，保障原油管道投产安全。

The Ripuluo crude oil pipeline has a total length of 798 km, with a maximum elevation difference of 132 m within a 6 km section along the line. It is commissioned by introducing oil after creating an isolated water section. During the commissioning process, issues such as gas accumulation at pipeline high-point and water accumulation at pipeline low-point are likely to occur in the pipe section with large elevation drop, which poses a threat to safe pipeline production. In this paper, the Ripuluo crude oil pipeline commissioning model is set up using OLGA software to analyze the pressure changes of the pumping stations during the pipeline commissioning process of water-replacing-gas and oil-replacing-water, the influence of different pipeline flow-rate and water-filled length on the pressure at the turning point, the liquid holdup and the low point water holdup. The results show that when the pipeline flow-rate is 1 440 m3/h and the minimum water-filled length reaches 70 km; the changes in the pressure at the pipeline turning point, and the liquid and water holdup at the low point can meet the safety requirements. It is recommended that if conditions permit, the water-filled length should be extended to the distance between the stations or the full pipeline length, which can further enhance the safety in commissioning process and trial operation. The research results can effectively guide the formulation of other pipeline commissioning plan and ensure the safety of pipeline’s commissioning.